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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC23B All Species: 22.73
Human Site: T257 Identified Species: 41.67
UniProt: Q15437 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15437 NP_006354.2 767 86479 T257 Q R D P W P V T Q G K R P L R
Chimpanzee Pan troglodytes XP_001140754 767 86435 T257 Q R D P W P V T Q G K R P L R
Rhesus Macaque Macaca mulatta XP_001091771 765 86128 P255 Q R D P W P V P Q G K R P L R
Dog Lupus familis XP_534332 767 86392 T257 Q R D P W P V T Q G K R P L R
Cat Felis silvestris
Mouse Mus musculus Q9D662 767 86419 T257 Q R D P W P V T Q G K R P L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513018 765 86087 P255 Q R D P W P V P Q G K R P L R
Chicken Gallus gallus Q5ZK03 767 86285 T257 Q R D P W P V T Q G K R P L R
Frog Xenopus laevis NP_001086405 741 83183 P257 Q R D P W P V P Q G K R P L R
Zebra Danio Brachydanio rerio Q7SZE5 765 86062 T255 Q R D P W P V T Q G K R P L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392515 768 85881 G258 Q R D P W P V G P G K R P L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780042 764 86244 N256 Q R D P W P V N A G K R P L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15303 768 85366 P253 S P D Q W S V P A G H R P L R
Red Bread Mold Neurospora crassa Q9C284 775 86260 A259 Q K D P W P V A G N L R A L R
Conservation
Percent
Protein Identity: 100 99.4 84.7 97.6 N.A. 97.1 N.A. N.A. 84.7 93 88.6 85.5 N.A. N.A. 73.5 N.A. 75.8
Protein Similarity: 100 99.6 92.5 98.9 N.A. 98.5 N.A. N.A. 92.4 96.6 92.1 91.6 N.A. N.A. 85.4 N.A. 85.6
P-Site Identity: 100 100 93.3 100 N.A. 100 N.A. N.A. 93.3 100 93.3 100 N.A. N.A. 86.6 N.A. 86.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 N.A. N.A. 93.3 100 93.3 100 N.A. N.A. 86.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51 57.9
Protein Similarity: N.A. N.A. N.A. N.A. 68.2 71.7
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 60
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 16 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 8 93 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 85 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 8 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 93 0 93 0 31 8 0 0 0 93 0 0 % P
% Gln: 93 0 0 8 0 0 0 0 70 0 0 0 0 0 0 % Q
% Arg: 0 85 0 0 0 0 0 0 0 0 0 100 0 0 100 % R
% Ser: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _